Tissue macrophage complexity as seen through a novel c-kit(Cre) fate mapping mouse

In this study, I addressed two main questions: first, how does microglia maintain its population; second, ontogenic origins of other tissue macrophages. In order to study the maintenance of microglia, I utlized two new cell ablation tools in order to deplete microglia: F4/80 and CD45-DTR mouse. I al...

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Bibliographic Details
Main Author: Sheng, Jianpeng
Other Authors: Klaus Erik Karjalainen
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/66369
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Institution: Nanyang Technological University
Language: English