Truncation of Cas9 protein for high performance target-specific genome engineering

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR associated proteins (Cas) system has emerged as a genome engineering tool with the programmable guide RNA sequence for specific gene targeting. However, for lentiviral based in vivo testing and engineering such as adeno-as...

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Bibliographic Details
Main Author: Wang, Fei
Other Authors: Tan Meng How
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72369
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Institution: Nanyang Technological University
Language: English