Lysosomal interplay between ubiquitination and phosphorylation regulates chaperone-mediated autophagy

• المؤلف الرئيسي: Rakshit, Moumita
• مؤلفون آخرون: Wong Siew Peng Esther
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2017
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/72725

Chaperone-mediated autophagy (CMA) is a selective autophagic pathway that degrades soluble cytosolic proteins. It utilizes a cascade of chaperones and co-chaperones to recognize and deliver the substrates to the lysosome for degradation. Basal CMA operates in all mammalian cells in order to maintain...