A study on X chromosome reactivation using iXist

Female mammals inactivate one of the two X chromosomes in each somatic cell in order to balance the X-linked gene dosage between females and males (X chromosome inactivation, XCI). This process is mediated by non-coding RNA X inactive specific transcript (Xist). Here, I show that, when embryonic ste...

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Bibliographic Details
Main Author: Lai, Lan Tian
Other Authors: Zhang Li-Feng
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72782
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Institution: Nanyang Technological University
Language: English
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