TGFBIp-associated corneal dystrophy : exploring structure-based drug development strategies for disease prevention and treatment

Corneal Dystrophies are a group of inherited disorders localized to various layers of the cornea that affect corneal transparency and visual acuity. The deposition of insoluble protein materials in the form of extracellular amyloid fibrils or intracellular cysts is pathognomonic. The gene associated...

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Bibliographic Details
Main Author: Anandalakshmi, Venkatraman
Other Authors: Konstantin Pervushin
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73264
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Institution: Nanyang Technological University
Language: English