Potential mechanism of xenobiotic seeding of TGFBIp fibrils and modified brain chaperones as therapy for TGFBI-associated corneal dystrophies

Transforming growth factor beta induced protein (TGFBIp) in the cornea undergoes proteolytic processing to produce peptides of uncertain physiological function with hereditary isoforms of the peptides giving rise to amyloidogenic corneal dystrophies (CD). This study explored the coacervation propens...

Full description

Saved in:
Bibliographic Details
Main Author: M K Abdul Rahim
Other Authors: Konstantin Pervushin
Format: Final Year Project
Language:English
Published: Nanyang Technological University 2022
Subjects:
Online Access:https://hdl.handle.net/10356/162946
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English