Sirolimus liposomal formulations : effects of Lipid Saturation/Surface charge on formulation stability and kinetics
Sirolimus is a macrolide compound commonly used as an anti-proliferant, as a result of its inhibitory effect on the mTOR pathway. Despite its therapeutic potential, its application remains limited due to its low water solubility, low stability and reduced bioavailability within the body. Since the d...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2018
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| Online Access: | http://hdl.handle.net/10356/73739 |
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| Institution: | Nanyang Technological University |
| Language: | English |