Characterization of the splicing function of pseudouridine Ψ5 in U1 small nuclear RNA

• المؤلف الرئيسي: Yong, Jing Yen
• مؤلفون آخرون: Francesc Xavier Roca Castella
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/74455

Pseudouridine (Ψ) is the major post-transcriptionally modified nucleotide in RNA. The 5’ end of U1 snRNA contains two evolutionarily conserved pseudouridines, Ψ5 and Ψ6, yet, their role in recognition of thousands of 5’ss variants remains to be established. Therefore, in our study, we investigated t...