Palladacycle-catalyzed asymmetric hydrophosphination of achiral heterobicyclic alkenes

• Main Author: Ong, Yew Jin
• Other Authors: Pullarkat A. Sumod
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Chemistry::Organic chemistry::Organic synthesis; DRNTU::Science::Chemistry::Organic chemistry::Organometallic compounds
• Online Access: http://hdl.handle.net/10356/76198
• Institution: Nanyang Technological University

Palladacycle-catalyzed asymmetric hydrophosphination of achiral heterobicyclic alkenes offers an unprecedented access towards novel chiral phosphine motifs. As an expansion of the substrate scope, four substrates that represent oxygen, nitrogen and carbon-bridged bicyclic alkenes were examined fo...