The MYC-independent effects of BET inhibitor JQ1 on super-enhancers in cancer

MYC overexpression plays an important role in cancer progression and is a common feature of many cancer types. One reason is due to the invasion of super-enhancer regions by MYC upstream of oncogenes, often resulting in activation of oncogenic pathways and poorer prognosis. The activation of oncogen...

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Bibliographic Details
Main Author: Chia, Boon Jun
Other Authors: Melissa Jane Fullwood
Format: Final Year Project
Language:English
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10356/77308
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Institution: Nanyang Technological University
Language: English