The MYC-independent effects of BET inhibitor JQ1 on super-enhancers in cancer
MYC overexpression plays an important role in cancer progression and is a common feature of many cancer types. One reason is due to the invasion of super-enhancer regions by MYC upstream of oncogenes, often resulting in activation of oncogenic pathways and poorer prognosis. The activation of oncogen...
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Main Author: | Chia, Boon Jun |
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Other Authors: | Melissa Jane Fullwood |
Format: | Final Year Project |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | http://hdl.handle.net/10356/77308 |
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Institution: | Nanyang Technological University |
Language: | English |
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