USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination
Ubiquitin modification of the TGF-β pathway components is emerging as a key mechanism of TGF-β pathway regulation. To limit TGF-β responses, TGF-β signaling is regulated through a negative feedback loop whereby the E3 ligase SMURF2 targets the TGF-β receptor (TβR) complex for ubiquitin-mediated degr...
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Main Authors: | Iyengar, Prasanna Vasudevan, Jaynes, Patrick, Rodon, Laura, Lama, Dilraj, Law, Kai Pong, Lim, Yoon Pin, Verma, Chandra, Seoane, Joan, Eichhorn, Pieter Johan Adam |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2015
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Online Access: | https://hdl.handle.net/10356/79335 http://hdl.handle.net/10220/38827 |
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Institution: | Nanyang Technological University |
Language: | English |
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