Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells

• Main Authors: Chang, Kenneth T. E., Preiser, Peter R., Loh, Eva, Chen, Qingfeng, Amaladoss, Anburaj, Ye, Weijian, Wong, Lan Hiong, Loo, Hooi Linn, Liu, Min, Dummler, Sara, Kong, Fang, Tan, Shu Qi, Tan, Thiam Chye, Dao, Ming, Suresh, Subra, Chen, Jianzhu
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2014
• 主題: DRNTU::Science::Biological sciences::Cytology
• 在線閱讀: https://hdl.handle.net/10356/79791; http://hdl.handle.net/10220/19421

Immunodeficient mouse–human chimeras provide a powerful approach to study host-specific pathogens, such as Plasmodium falciparum that causes human malaria. Supplementation of immunodeficient mice with human RBCs supports infection by human Plasmodium parasites, but these mice lack the human immune s...