Principles of electrostatic interactions and self-assembly in lipid/peptide/DNA systems: Applications to gene delivery

• Main Authors: Berezhnoy, Nikolay V., Korolev, Nikolay, Nordenskiöld, Lars
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Chromatin; DNA condensation
• Online Access: https://hdl.handle.net/10356/81645; http://hdl.handle.net/10220/40870
• Institution: Nanyang Technological University

Recently, great progress has been achieved in development of a wide variety of formulations for gene delivery in vitro and in vivo, which include lipids, peptides and DNA (LPD). Additionally, application of natural histone–DNA complexes (chromatin) in combination with transfection lipids has been su...