Sulfoxidation of alkenes and alkynes with NFSI as a radical initiator and selective oxidant

• Main Authors: Zhang, Yuexia, Wong, Zeng Rong, Wu, Xingxing, Lauw, Sherman Jun Liang, Huang, Xuan, Webster, Richard David, Chi, Yonggui Robin
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Sulfoxides; N-Fluorobenzenesulfonimide
• Online Access: https://hdl.handle.net/10356/82060; http://hdl.handle.net/10220/43495
• Institution: Nanyang Technological University

Sulfoxides are important functional molecules. We develop a short-route (one-pot) synthesis of this class of molecules by reacting thiols with alkenes or alkynes under mild and metal-free conditions. N-Fluorobenzenesulfonimide (NFSI) is used to play dual roles: as a radical initiator for a thiol–ene...