Studies on the synthesis of the lasubine alkaloids

Formal syntheses of lasubine II and subcosine II have been completed by the synthesis of epi-lasubine II. The synthesis involves diastereoselective allylation of a methoxy isoxazolidine and a tandem hydrogenation process leading stereoselectively to a trisubstituted piperidine.

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Bibliographic Details
Main Authors: Simon, Oliver, Nur Filza Mohamed Aslam, Bates, Roderick Wayland
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/83262
http://hdl.handle.net/10220/50081
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Institution: Nanyang Technological University
Language: English