Synthesis of azimic acid using hydroformylation

A synthesis of the alkaloid azimic acid has been achieved using double hydroformylation with a single tandem condensation to form the six membered ring. The oxygen substituent was introduced by diastereoselective dihydroxylation, cis to the existing alkyl substituent. The methyl substituent was intr...

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Bibliographic Details
Main Authors: Bates, Roderick Wayland, Kasinathan, Sivarajan
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/99815
http://hdl.handle.net/10220/17781
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Institution: Nanyang Technological University
Language: English