Synthesis of azimic acid using hydroformylation

• المؤلفون الرئيسيون: Bates, Roderick Wayland, Kasinathan, Sivarajan
• مؤلفون آخرون: School of Physical and Mathematical Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: Science::Chemistry; Piperidine; Alkaloid
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/99815; http://hdl.handle.net/10220/17781
• المؤسسة: Nanyang Technological University

A synthesis of the alkaloid azimic acid has been achieved using double hydroformylation with a single tandem condensation to form the six membered ring. The oxygen substituent was introduced by diastereoselective dihydroxylation, cis to the existing alkyl substituent. The methyl substituent was intr...