A synthesis of 5-hydroxysedamine using hydroformylation

A synthesis of 5-hydroxysedamine, a Sedum alkaloid, has been completed using N,O-heterocycle chemistry to establish the aminoalcohol structure, hydroformylation to form the piperidine ring and diastereoselective dihydroxylation to introduce the 5-hydroxy group.

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Bibliographic Details
Main Authors: Bates, Roderick Wayland, Nur Filza Mohamed Aslam, Tang, Chi H., Simon, Oliver
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/103108
http://hdl.handle.net/10220/24359
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Institution: Nanyang Technological University
Language: English