Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides

• Main Authors: Braun, Katharina, Pochert, Alexander, Lindén, Mika, Davoudi, Mina, Schmidtchen, Artur, Nordström, Randi, Malmsten, Martin
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Subjects: membrane; antimicrobial peptides
• Online Access: https://hdl.handle.net/10356/84025; http://hdl.handle.net/10220/41593
• Institution: Nanyang Technological University

Membrane interactions are critical for the successful use of mesoporous silica nanoparticles as delivery systems for antimicrobial peptides (AMPs). In order to elucidate these, we here investigate effects of nanoparticle charge and porosity on AMP loading and release, as well as consequences of this...