Safety and feasibility of intrastromal injection of cultivated human corneal stromal keratocytes as cell-based therapy for corneal opacities

Safety and feasibility of intrastromal injection of cultivated human corneal stromal keratocytes as cell-based therapy for corneal opacities

Purpose: To evaluate the safety and feasibility of intrastromal injection of human corneal stromal keratocytes (CSKs) and its therapeutic effect on a rodent early corneal opacity model. Methods: Twelve research-grade donor corneas were used in primary culture to generate quiescent CSKs and activated...

Saved in:

書目詳細資料
Main Authors:	Yam, Gary Hin-Fai, Fuest, Matthias, Nur Zahirah M. Yusoff, Mehta, Jodhbir Singh, Goh, Tze-Wei, Bandeira, Francisco, Setiawan, Melina, Seah, Xin-Yi, Lwin, Nyein-Chan, Stanzel, Tisha P., Ong, Hon-Shing
其他作者:	School of Materials Science & Engineering
格式:	Article
語言:	English
出版:	2019
主題:	Science::Medicine Intrastromal Injection Corneal Opacities
在線閱讀:	https://hdl.handle.net/10356/84634 http://hdl.handle.net/10220/49158
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!
機構:	Nanyang Technological University
語言:	English

相似書籍

Isolation and propagation of human corneal stromal keratocytes for tissue engineering and cell therapy
由: Nur Zahirah Binte M. Yusoff, et al.
出版: (2023)

Nerve regeneration by human corneal stromal keratocytes and stromal fibroblasts
由: Yam, Gary Hin-Fai, et al.
出版: (2017)

Nerve regeneration by human corneal stromal keratocytes and stromal fibroblasts
由: Yam, G.H.-F, et al.
出版: (2020)

Decellularization of human stromal refractive lenticules for corneal tissue engineering
由: Yam, Gary Hin-Fai, et al.
出版: (2018)

Corneal stromal fibroblasts cell derived nanovesicles (CDN) in acute corneal haze context
由: Then, Ryan Yong Jian
出版: (2024)

Effect of corneal stromal lenticule customization on neurite distribution and excitatory property
由: Yam, G.H.-F., et al.
出版: (2022)

Postnatal periodontal ligament as a novel adult stem cell source for regenerative corneal cell therapy
由: Yam, Gary Hin-Fai, et al.
出版: (2018)

Human corneal keratocyte response to micro-and nano-gratings on chitosan and PDMS
由: Koo, S., et al.
出版: (2014)

Corneal inlays for presbyopia explanted due to corneal haze
由: Ong, Hon Shing, et al.
出版: (2019)

Cellular therapy of corneal epithelial defect by adipose mesenchymal stem cell-derived epithelial progenitors
由: Bandeira, Francisco, et al.
出版: (2021)

Human platelet lysate as a replacement for fetal bovine serum in human corneal stromal keratocyte and fibroblast culture
由: Seidelmann, Nina, et al.
出版: (2022)

Human platelet lysate as a replacement for fetal bovine serum in human corneal stromal keratocyte and fibroblast culture
由: Seidelmann, Nina, et al.
出版: (2022)

Characterization of human transition zone reveals a putative progenitor-enriched niche of corneal endothelium
由: Yam, Gary Hin-Fai, et al.
出版: (2020)

Repeatability and reproducibility of corneal biometric measurements using the visante omni and a rabbit experimental model of post-surgical corneal ectasia
由: Liu, Yu-Chi, et al.
出版: (2020)

Decellularization of human stromal refractive lenticules for corneal tissue engineering
由: Yam, G.H.-F, et al.
出版: (2020)

Mediators of corneal haze following implantation of presbyopic corneal inlays
由: Fenner, B.J., et al.
出版: (2021)

Evaluation of a Micro-Optical Coherence Tomography for the Corneal Endothelium in an Animal Model
由: Ang, Marcus, et al.
出版: (2017)

A Novel Approach of Harvesting Viable Single Cells from Donor Corneal Endothelium for Cell-Injection Therapy
由: Ong, H.S., et al.
出版: (2021)

Human corneal endothelial cell expansion for corneal endothelium transplantation: An overview
由: Peh, G.S.L., et al.
出版: (2014)

Biological corneal inlay for presbyopia derived from small incision lenticule extraction (SMILE)
由: Liu, Yu-Chi, et al.
出版: (2018)

Early visibility of cellular aggregates and changes in central corneal thickness as predictors of successful corneal endothelial cell injection therapy
由: Wong, Evan N., et al.
出版: (2023)

Near infra-red labelling and tracking of corneal endothelial cells in-vivo
由: Bhogal, Maninder, et al.
出版: (2023)

Generation of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindness
由: Ding, Vanessa, et al.
出版: (2016)

Regenerative capacity of the corneal transition zone for endothelial cell therapy
由: Sie, Nicole Ming, et al.
出版: (2021)

Corneal Cross-Linking: The Evolution of Treatment for Corneal Diseases
由: Wu, Duoduo, et al.
出版: (2022)

Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms
由: Petznick, A., et al.
出版: (2014)

Regulatory compliant tissue-engineered human corneal endothelial grafts restore corneal function of rabbits with bullous keratopathy
由: Peh, Gary S. L., et al.
出版: (2018)

Recurrent corneal erosion after laser in situ keratomileusis
由: Ti, S.-E., et al.
出版: (2016)

A rich OPAC user interface with AJAX
由: Gozali, J.P., et al.
出版: (2013)

Characterization of Human Transition Zone Reveals a Putative Progenitor-Enriched Niche of Corneal Endothelium
由: Yam, G.H.-F., et al.
出版: (2021)

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells
由: Lovatt, Matthew, et al.
出版: (2021)

Early Visibility of Cellular Aggregates and Changes in Central Corneal Thickness as Predictors of Successful Corneal Endothelial Cell Injection Therapy
由: Wong, Evan N, et al.
出版: (2023)

Optical coherence tomography angiography imaging to monitor anti-VEGF treatment of corneal vascularization in a rabbit model
由: Devarajan, Kavya, et al.
出版: (2020)

Spontaneous Corneal Perforation in Premature Infants
由: Wong, J.S., et al.
出版: (2016)

Effects of topical heparin, antivenom, tetracycline and dexamethasone treatment in corneal injury resulting from the venom of the black spitting cobra (Naja sumatrana), in a rabbit model
由: Cham, G., et al.
出版: (2011)

Functional reconstruction of corneal endothelium using nanotopography for tissue-engineering applications
由: Teo, B.K.K., et al.
出版: (2014)

Automatic opacity detection in retro-illumination images for cortical cataract diagnosis
由: Li, H., et al.
出版: (2011)

Modulation of the in vitro microenvironment of corneal keratocytes using macromolecular crowding
由: Kumar, P., et al.
出版: (2014)

Effect of Intraoperative Corneal Stromal Pocket Irrigation in Small Incision Lenticule Extraction
由: Liu, Yu-Chi, et al.
出版: (2015)

Parametric timed model checking for guaranteeing timed opacity
由: ANDRÉ, Étienne, et al.
出版: (2019)