Water-Bridge Mediates Recognition of mRNA Cap in eIF4E
Ligand binding pockets in proteins contain water molecules, which play important roles in modulating protein-ligand interactions. Available crystallographic data for the 5′ mRNA cap-binding pocket of the translation initiation factor protein eIF4E shows several structurally conserved waters, which a...
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Main Authors: | Lama, Dilraj, Pradhan, Mohan R., Brown, Christopher J., Eapen, Rohan S., Joseph, Thomas L., Kwoh, Chee-Keong, Lane, David P., Verma, Chandra Shekhar |
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Other Authors: | School of Computer Science and Engineering |
Format: | Article |
Language: | English |
Published: |
2017
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/84992 http://hdl.handle.net/10220/42071 |
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Institution: | Nanyang Technological University |
Language: | English |
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