Kinetic and cross-sectional studies on the genesis of hypoargininemia in severe pediatric plasmodium falciparum malaria

• المؤلفون الرئيسيون: Florence, Salvatore M., Kalingonji, Ayam R., Yeo, Tsin Wen, Lopansri, Bert K., Thompson, J. Will, Young, Sarah, Millington, David S., Weinberg, J. Brice, Granger, Donald L., Mwaikambo, Esther D., Matthew, P. Rubach, Zhang, Haoyue, Mukemba, Jackson P., Anstey, Nicholas M.
• مؤلفون آخرون: Adams, John H.
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Arginine; DRNTU::Science::Medicine; Plasmodium Falciparum
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/85330; http://hdl.handle.net/10220/48465

The low bioavailability of nitric oxide (NO) and its precursor, arginine, contributes to the microvascular pathophysiology of severe falciparum malaria. To better characterize the mechanisms underlying hypoargininemia in severe malaria, we measured the plasma concentrations of amino acids involved i...