De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

• Main Authors: Ding, Chunming, Lim, Yen Ching, Chia, Sook Yoong, Walet, Arcinas Camille Esther, Xu, Shaohai, Lo, Alice Kinyui, Zhao, Yanling, Zhu, Dewen, Shan, Zhihui, Chen, Qingfeng, Leow, Melvin Khee-Shing, Xu, Dan, Sun, Lei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Adipose; Brown Adipogenesis
• Online Access: https://hdl.handle.net/10356/87029; http://hdl.handle.net/10220/45300
• Institution: Nanyang Technological University

Obesity has emerged as an alarming health crisis due to its association with metabolic risk factors such as diabetes, dyslipidemia, and hypertension. Recent work has demonstrated the multifaceted roles of lncRNAs in regulating mouse adipose development, but their implication in human adipocytes rema...