From the unfolded protein response to metabolic diseases – lipids under the spotlight

The unfolded protein response (UPR) is classically viewed as a stress response pathway to maintain protein homeostasis at the endoplasmic reticulum (ER). However, it has recently emerged that the UPR can be directly activated by lipid perturbation, independently of misfolded proteins. Comprising pri...

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Bibliographic Details
Main Authors: Ho, Nurulain, Xu, Chengchao, Thibault, Guillaume
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/87971
http://hdl.handle.net/10220/45592
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Institution: Nanyang Technological University
Language: English