Lipid bilayer stress and proteotoxic stress-induced unfolded protein response deploy divergent transcriptional and non-transcriptional programmes
The unfolded protein response (UPR) is activated by endoplasmic reticulum (ER) stress and is designed to restorecellular homeostasis through multiple intracellular signalling pathways. In mammals, the UPR programmeregulates the expression of hundreds of genes in response to signalling from ATF6, IRE...
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/136602 |
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| Institution: | Nanyang Technological University |
| Language: | English |