Lysine methylation of progesterone receptor at activation function 1 regulates both ligand-independent activity and ligand sensitivity of the receptor

Progesterone receptor (PR) exists in two isoforms, PRA and PRB, and both contain activation functions AF-1 and AF-2. It is believed that AF-1 is primarily responsible for the ligand-independent activity, whereas AF-2 mediates ligand-dependent PR activation. Although more than a dozen post-translatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Chung, Hwa Hwa, Sze, Siu Kwan, Woo, Amanda Rui En, Sun, Yang, Sim, Kae Hwan, Dong, Xue Ming, Lin, Valerie Chun-Ling
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/88378
http://hdl.handle.net/10220/45806
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
Be the first to leave a comment!
You must be logged in first