Asymmetric dimethylarginine in adult falciparum malaria: relationships with disease severity, antimalarial treatment, hemolysis, and inflammation

Asymmetric dimethylarginine in adult falciparum malaria: relationships with disease severity, antimalarial treatment, hemolysis, and inflammation

Background: Endothelial nitric oxide (NO) bioavailability is impaired in severe falciparum malaria (SM). Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of NO synthase (NOS), contributes to endothelial dysfunction and is associated with mortality in adults with falciparum malaria. Howeve...

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Bibliographic Details
Main Authors: Barber, Bridget E., William, Timothy, Grigg, Matthew J., Parameswaran, Uma, Piera, Kim A., Yeo, Tsin Wen, Anstey, Nicholas M.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Arginine
DRNTU::Science::Medicine
ADMA
Online Access:https://hdl.handle.net/10356/89025
http://hdl.handle.net/10220/46994
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89025
http://hdl.handle.net/10220/46994

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