Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously and regulates actin cytoskeleton remodeling. In order to characterize the role of N-WASP in epidermal homeostasis and cutaneous biology, we generated conditional N-WASP knockout mouse using CK14-cre (cytokeratin 14) to ablate...

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Bibliographic Details
Main Authors: Kalailingam, Pazhanichamy, Tan, Hui Bing, Jain, Neeraj, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
Actin
Genetics
Online Access:https://hdl.handle.net/10356/89475
http://hdl.handle.net/10220/44984
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89475
http://hdl.handle.net/10220/44984

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