Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli

• Main Authors: Wang, Haibo, Yan, Aixin, Liu, Zhigang, Yang, Xinming, Xu, Zeling, Wang, Yuchuan, Wang, Runming, Hu, Ligang, Xia, Wei, Tang, Huiru, Wang, Yulan, Li, Hongyan, Sun, Hongzhe, Mohamad Koohi-Moghadam
• Other Authors: Sourjik, Victor
• Format: Article
• Language: English
• Published: 2019
• Subjects: Molecular Mechanism; Antimicrobial; Science::Medicine
• Online Access: https://hdl.handle.net/10356/90018; http://hdl.handle.net/10220/49373
• Institution: Nanyang Technological University

Despite the broad-spectrum antimicrobial activities of silver, its internal usage is restricted, owing to the toxicity. Strategies to enhance its efficacy are highly desirable but rely heavily on the understanding of its molecular mechanism of action. However, up to now, no direct silver-targeting p...