An alternative phosphorylation switch in integrin β2 (CD18) tail for Dok1 binding

Integrins are involved in cell migration and adhesion. A large number of proteins interact with the cytoplasmic tails of integrins. Dok1 is a negative regulator of integrin activation and it binds to the phosphorylated membrane proximal NxxY motif in a number of integrin β tails. The β tail of the β...

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Bibliographic Details
Main Authors: Gupta, Sebanti, Chit, Joel Chia-Yeong, Feng, Chen, Bhunia, Anirban, Tan, Suet-Mien, Bhattacharjya, Surajit
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
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Online Access:https://hdl.handle.net/10356/93744
http://hdl.handle.net/10220/38329
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Institution: Nanyang Technological University
Language: English

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