Solvent effect on the folding dynamics and structure of E6-associated protein characterized from Ab initio protein folding simulations

• Main Authors: Xu, Zhijun, Lazim, Raudah, Sun, Tiedong, Mei, Ye, Zhang, Dawei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/95243; http://hdl.handle.net/10220/9339
• Institution: Nanyang Technological University

Solvent effect on protein conformation and folding mechanism of E6-associated protein (E6ap) peptide are investigated using a recently developed charge update scheme termed as adaptive hydrogen bond-specific charge (AHBC). On the basis of the close agreement between the calculated helix contents fro...