Formation of pearl-necklace monomorphic G-quadruplexes in the human CEB25 minisatellite

• Main Authors: Amrane, Samir, Adrian, Michael, Heddi, Brahim, Serero, Alexandre, Nicolas, Alain, Mergny, Jean-Louis, Phan, Anh Tuân
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/95807; http://hdl.handle.net/10220/11207
• Institution: Nanyang Technological University

CEB25 is a human minisatellite locus, composed of slightly polymorphic 52-nucleotide (nt) tandem repeats. Genetically, most if not all individuals of the human population are heterozygous, carrying alleles ranging from 0.5 to 20 kb, maintained by mendelian inheritance but also subject to germline in...