Copper-catalyzed aerobic [3+2] : annulation of N-alkenyl amidines

A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines. These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride.

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Bibliographic Details
Main Authors: Wang, Yi-Feng, Zhu, Xu, Chiba, Shunsuke
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/95814
http://hdl.handle.net/10220/11280
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Institution: Nanyang Technological University
Language: English