Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds

A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.

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Bibliographic Details
Main Authors: Tang, Qiang, Chen, Xingkuan, Tiwari, Bhoopendra, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/97259
http://hdl.handle.net/10220/10633
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Institution: Nanyang Technological University
Language: English