Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds

A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.

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Main Authors: Tang, Qiang, Chen, Xingkuan, Tiwari, Bhoopendra, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/97259
http://hdl.handle.net/10220/10633
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-972592020-03-07T12:34:42Z Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds Tang, Qiang Chen, Xingkuan Tiwari, Bhoopendra Chi, Robin Yonggui School of Physical and Mathematical Sciences A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields. 2013-06-25T06:32:56Z 2019-12-06T19:40:39Z 2013-06-25T06:32:56Z 2019-12-06T19:40:39Z 2012 2012 Journal Article Tang, Q., Chen, X., Tiwari, B., & Chi, Y. R. (2012). Addition of Indoles to Oxyallyl Cations for Facile Access to α-Indole Carbonyl Compounds. Organic Letters, 14(7), 1922-1925. 1523-7060 https://hdl.handle.net/10356/97259 http://hdl.handle.net/10220/10633 10.1021/ol300591z 173622 en Organic letters © 2012 American Chemical Society.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description A direct coupling of unprotected indoles and α-halo ketones via in situ generated oxyallyl cation intermediates is described. The reactions efficiently afford α-indole carbonyl compounds with good to quantitative yields.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Tang, Qiang
Chen, Xingkuan
Tiwari, Bhoopendra
Chi, Robin Yonggui
format Article
author Tang, Qiang
Chen, Xingkuan
Tiwari, Bhoopendra
Chi, Robin Yonggui
spellingShingle Tang, Qiang
Chen, Xingkuan
Tiwari, Bhoopendra
Chi, Robin Yonggui
Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
author_sort Tang, Qiang
title Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
title_short Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
title_full Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
title_fullStr Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
title_full_unstemmed Addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
title_sort addition of indoles to oxyallyl cations for facile access to α-indole carbonyl compounds
publishDate 2013
url https://hdl.handle.net/10356/97259
http://hdl.handle.net/10220/10633
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