Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts

Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts

The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines.

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Main Authors: Hao, Lin, Du, Yu, Lv, Hui, Chen, Xingkuan, Jiang, Huishen, Shao, Yaling, Chi, Robin Yonggui
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/97284
http://hdl.handle.net/10220/10637
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-972842020-03-07T12:34:43Z Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts Hao, Lin Du, Yu Lv, Hui Chen, Xingkuan Jiang, Huishen Shao, Yaling Chi, Robin Yonggui School of Physical and Mathematical Sciences The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines. 2013-06-25T06:40:51Z 2019-12-06T19:40:53Z 2013-06-25T06:40:51Z 2019-12-06T19:40:53Z 2012 2012 Journal Article Hao, L., Du, Y., Lv, H., Chen, X., Jiang, H., Shao, Y., et al. (2012). Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents via N-Heterocyclic Carbene Catalysts. Organic Letters, 14(8), 2154-2157. 1523-7060 https://hdl.handle.net/10356/97284 http://hdl.handle.net/10220/10637 10.1021/ol300676w 164430 en Organic letters © 2012 American Chemical Society.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
description The first N-Heterocyclic Carbene (NHC) mediated activation of stable carboxylate esters to generate enolate intermediates is disclosed. The catalytically generated arylacetic ester enolates undergo enantioselective reactions with α,β-unsaturated imines.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Hao, Lin
Du, Yu
Lv, Hui
Chen, Xingkuan
Jiang, Huishen
Shao, Yaling
Chi, Robin Yonggui
format Article
author Hao, Lin
Du, Yu
Lv, Hui
Chen, Xingkuan
Jiang, Huishen
Shao, Yaling
Chi, Robin Yonggui
spellingShingle Hao, Lin
Du, Yu
Lv, Hui
Chen, Xingkuan
Jiang, Huishen
Shao, Yaling
Chi, Robin Yonggui
Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
author_sort Hao, Lin
title Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
title_short Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
title_full Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
title_fullStr Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
title_full_unstemmed Enantioselective activation of stable carboxylate esters as enolate equivalents via N-heterocyclic carbene catalysts
title_sort enantioselective activation of stable carboxylate esters as enolate equivalents via n-heterocyclic carbene catalysts
publishDate 2013
url https://hdl.handle.net/10356/97284
http://hdl.handle.net/10220/10637
_version_ 1681039526421594112

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