Integration of genomic and epigenomic features to predict meiotic recombination hotspots in human and mouse

• Main Authors: Przytycka, Teresa M., Wu, Min, Kwoh, Chee Keong, Li, Jing, Zheng, Jie
• 其他作者: School of Computer Engineering
• 格式: Conference or Workshop Item
• 語言: English
• 出版: 2013
• 主題: DRNTU::Engineering::Computer science and engineering
• 在線閱讀: https://hdl.handle.net/10356/97678; http://hdl.handle.net/10220/11871

The regulatory mechanism of meiotic recombination hotspots is a fundamental problem in biology, with broad impacts on areas ranging from disease study to evolution. Recently, many genomic and epigenomic features have been associated with recombination hotspots, but none of them can explain hotspots...