Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations

Recent experiments in function mechanism study reported that a pH low-insertion peptide (pHLIP) can insert into a zwitterionic palmitoyloleoylphosphatidylcholine (POPC) lipid bilayer at acidic pH while binding to the bilayer surface at basic pH. However, the atomic details of the pH-dependent intera...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhang, Yun, Deng, Yonghua, Qian, Zhenyu, Luo, Yin, Mu, Yuguang, Wei, Guanghong
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/98126
http://hdl.handle.net/10220/12244
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English