Membrane binding and insertion of a pHLIP peptide studied by all-atom molecular dynamics simulations
Recent experiments in function mechanism study reported that a pH low-insertion peptide (pHLIP) can insert into a zwitterionic palmitoyloleoylphosphatidylcholine (POPC) lipid bilayer at acidic pH while binding to the bilayer surface at basic pH. However, the atomic details of the pH-dependent intera...
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Main Authors: | Zhang, Yun, Deng, Yonghua, Qian, Zhenyu, Luo, Yin, Mu, Yuguang, Wei, Guanghong |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/98126 http://hdl.handle.net/10220/12244 |
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Institution: | Nanyang Technological University |
Language: | English |
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