Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31

• Main Authors: Löw, Christian, Moberg, Per, Guettou, Fatma, Maddi, Karthik, Nordlund, Pär, Quistgaard, Esben M.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/98129; http://hdl.handle.net/10220/13322
• Institution: Nanyang Technological University

Two members of the B-cell associated 31 (BAP31) family are found in humans; BAP29 and BAP31. These are ubiquitously expressed receptors residing in the endoplasmic reticulum. BAP31 functions in sorting of membrane proteins and in caspase-8 mediated apoptosis, while BAP29 appears to mainly corroborat...