Tf 2 NH-catalyzed amide synthesis from vinyl azides and alcohols

• Main Authors: Zhang, Feng-Lian, Zhu, Xu, Chiba, Shunsuke
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Chemistry::Organic chemistry
• Online Access: https://hdl.handle.net/10356/98598; http://hdl.handle.net/10220/38585
• Institution: Nanyang Technological University

Triflimide (Tf2NH) specifically catalyzed reactions of alcohols and vinyl azides, enabling efficient construction of amides with C–C bond formation through nucleophilic attack of vinyl azides onto the putative carbocation intermediates derived from alcohols are described.