Study on the oiling-out and crystallization for the purification of idebenone

Oiling-out, also termed as demixing or liquid–liquid phase separation (LLPS), frequently occurs in the crystallization process of pharmaceuticals and normally results in slow crystal growth, uncontrollable crystal morphology, and low purity of products. In this work, the oiling-out and cooling cryst...

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Bibliographic Details
Main Authors: Lu, Jie, Li, Yi-Ping, Wang, Jing, Li, Zhen, Rohani, Sohrab, Ching, Chi Bun
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/99038
http://hdl.handle.net/10220/17124
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Institution: Nanyang Technological University
Language: English
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