A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
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Main Authors: | , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 |
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Institution: | Nanyang Technological University |
Language: | English |