A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines

A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.

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Bibliographic Details
Main Authors:	Chen, Ke, Pullarkat, Sumod A.
Other Authors:	School of Physical and Mathematical Sciences
Format:	Article
Language:	English
Published:	2013
Subjects:	DRNTU::Science::Chemistry::Organic chemistry
Online Access:	https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-991762020-03-07T12:31:22Z A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines Chen, Ke Pullarkat, Sumod A. School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields. 2013-10-31T07:44:01Z 2019-12-06T20:04:08Z 2013-10-31T07:44:01Z 2019-12-06T20:04:08Z 2012 2012 Journal Article Chen, K., & Pullarkat, S. A. (2012). A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines. Organic & biomolecular chemistry, 10(32), 6600-6606. https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 10.1039/c2ob25854d en Organic & biomolecular chemistry
institution	Nanyang Technological University
building	NTU Library
country	Singapore
collection	DR-NTU
language	English
topic	DRNTU::Science::Chemistry::Organic chemistry
spellingShingle	DRNTU::Science::Chemistry::Organic chemistry Chen, Ke Pullarkat, Sumod A. A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
description	A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
author2	School of Physical and Mathematical Sciences
author_facet	School of Physical and Mathematical Sciences Chen, Ke Pullarkat, Sumod A.
format	Article
author	Chen, Ke Pullarkat, Sumod A.
author_sort	Chen, Ke
title	A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
title_short	A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
title_full	A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
title_fullStr	A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
title_full_unstemmed	A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
title_sort	tandem heck–aza-michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
publishDate	2013
url	https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155
_version_	1681038618890600448

A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines

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