A tandem Heck–aza-Michael addition protocol for the one-pot synthesis of isoindolines from unprotected amines
A palladacycle-catalyzed tandem Heck-intramolecular aza-Michael reaction protocol has been developed for the one-pot synthesis of 1-substituted isoindolines from N-unprotected 2-bromobenzylamines and acrylates with high yields.
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| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/99176 http://hdl.handle.net/10220/17155 |
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| Institution: | Nanyang Technological University |
| Language: | English |