Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization–alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives.
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/99216 http://hdl.handle.net/10220/17156 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization–alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives. |
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