Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols

A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization–alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives.

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Main Authors:	Xu, Chang., Murugan, Vinod K., Pullarkat, Sumod A.
Other Authors:	School of Physical and Mathematical Sciences
Format:	Article
Language:	English
Published:	2013
Subjects:	DRNTU::Science::Chemistry::Organic chemistry
Online Access:	https://hdl.handle.net/10356/99216 http://hdl.handle.net/10220/17156
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Institution:	Nanyang Technological University
Language:	English

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spelling	sg-ntu-dr.10356-992162020-03-07T12:31:29Z Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols Xu, Chang. Murugan, Vinod K. Pullarkat, Sumod A. School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization–alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives. 2013-10-31T07:47:50Z 2019-12-06T20:04:45Z 2013-10-31T07:47:50Z 2019-12-06T20:04:45Z 2012 2012 Journal Article Xu, C., Murugan, V. K., & Pullarkat, S. A. (2012). Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols. Organic & biomolecular chemistry, 10(19), 3875-3881. https://hdl.handle.net/10356/99216 http://hdl.handle.net/10220/17156 10.1039/c2ob25379h en Organic & biomolecular chemistry
institution	Nanyang Technological University
building	NTU Library
country	Singapore
collection	DR-NTU
language	English
topic	DRNTU::Science::Chemistry::Organic chemistry
spellingShingle	DRNTU::Science::Chemistry::Organic chemistry Xu, Chang. Murugan, Vinod K. Pullarkat, Sumod A. Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
description	A practical and efficient protocol for the one-pot synthesis of 2,3-substituted indoles was developed via a palladacycle catalyzed domino cyclization–alkylation reaction involving 2-alkynylanilines and allylic alcohols under mild conditions without any additives.
author2	School of Physical and Mathematical Sciences
author_facet	School of Physical and Mathematical Sciences Xu, Chang. Murugan, Vinod K. Pullarkat, Sumod A.
format	Article
author	Xu, Chang. Murugan, Vinod K. Pullarkat, Sumod A.
author_sort	Xu, Chang.
title	Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
title_short	Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
title_full	Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
title_fullStr	Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
title_full_unstemmed	Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
title_sort	domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols
publishDate	2013
url	https://hdl.handle.net/10356/99216 http://hdl.handle.net/10220/17156
_version_	1681038952936505344

Domino cyclization–alkylation protocol for the synthesis of 2,3-functionalized indoles from o-alkynylanilines and allylic alcohols

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