Aptamer-based multicolor fluorescent gold nanoprobes for multiplex detection in homogeneous solution

• Main Authors: Fan, Chunhai, Zhang, Juan, Wang, Lihua, Zhang, Hua, Boey, Freddy Yin Chiang, Song, Shiping
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2012
• Subjects: DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/99641; http://hdl.handle.net/10220/8584
• Institution: Nanyang Technological University

The design of a novel multicolor fluorescent gold nanoprobe for homogeneous detection of small-molecule targets is reported, which combines the specific binding abilities of aptamers with the ultrahigh quenching ability of gold nanoparticles (AuNPs). Dye-tagged aptamers and their complementary seque...