Synthesis of cephalosporin-3′-diazeniumdiolates : biofilm dispersing NO-donor prodrugs activated by β-lactamase
Use of biofilm dispersing NO-donor compounds in combination with antibiotics has emerged as a promising new strategy for treating drug-resistant bacterial biofilm infections. This paper details the synthesis and preliminary evaluation of six cephalosporin-3′-diazeniumdiolates as biofilm-targeted NO-...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/99731 http://hdl.handle.net/10220/17528 |
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| Institution: | Nanyang Technological University |
| Language: | English |